LA JOLLA PHARMACEUTICAL CO NASDAQ:LJPC |COM (Q)  SIC: 2836 (Biological Products, (No Disgnostic Substances))

* Total Outstanding: 39.6 million shares (as of 2008-05-13)

<Top 5 Institutional Holders> Institution Shs Held Date % IG INVESTMENT MANAGEMENT LTD 1,040,979 12/31/08 2.63 DIKER MANAGEMENT LLC 716,902 12/31/08 1.81 DIMENSIONAL FUND ADVISORS INC 636,099 12/31/08 1.60 VANGUARD GROUP INC 445,881 12/31/08 1.12 Aletheia Research & Management, Inc. 434,461 12/31/08 1.10

<5% Owners' Recent Filings> 5% Owner Shs Held Date % N/A - - - <Insiders' Recent Filings> Insider Shs Held Date % BIOMARIN PHARMACEUTICAL INC 4,466,387 06/19/09 11.27 Frazier Healthcare V, LP 5,470,555 02/24/09 13.80